The Miami Dolphins and Jacksonville Jaguars got Week 3 started on Thursday night, as Brian Flores' squad secured their first victory of the season -- a 31-13 beatdown on "Thursday Night Football." The Jaguars were surely not the same team without DJ Chark on the field, who sat out due to chest and back injuries. He will not be the only important player to miss Week 3, however, and we are here to break down all of those details for you.
One team that was especially hit hard by injuries this past week was the San Francisco 49ers, as Nick Mullens will be under center this Sunday against the New York Giants, and won't have star tight end George Kittle to throw to either.
Below, we will break down every team's final injury report as we head into this weekend. All odds are courtesy of William Hill Sportsbook.
Bengals at Eagles (-4.5)
- Bengals: DT Geno Atkins (shoulder) OUT; DT Mike Daniels (groin), S Shawn Williams (calf) QUESTIONABLE
- Eagles: WR Alshon Jeffery (foot), WR Jalen Reagor (thumb), S Rudy Ford (groin) OUT; DT Fletcher Cox (abdomen) QUESTIONABLE
Atkins won't be making his season debut this week as that shoulder injury suffered during the last week of training camp has kept him out. The Bengals will need Daniels to suit up in Atkins' absence, but he did not practice all week. Cincinnati gave up over 200 rushing yards to Cleveland as a result of the pair of defensive tackles not playing and could face a long afternoon facing Miles Sanders without either one of them.
While Jeffery returned to practice this week for the first time, head coach Doug Pederson says he's not yet ready to suit up for a regular-season game. Additionally, the Eagles will also be without rookie wideout Jalen Reagor against the Bengals due to a thumb injury. Cox was a limited participant in practice Friday and all signs indicate he'll be available for Sunday's game.
49ers (-3.5) at Giants
- 49ers: QB Jimmy Garoppolo (ankle), RB Raheem Mostert (knee), RB Tevin Coleman (knee), DE Dee Ford (back), TE George Kittle (knee), LB Dre Greenlaw (quad) OUT; CB Ahkello Witherspoon (hamstring) QUESTIONABLE
- Giants: DB Adrian Colbert (quad) DOUBTFUL; CB Brandon Williams (groin) QUESTIONABLE
The Giants are getting a beat-up 49ers team this Sunday, as they were absolutely ravaged by injuries at MetLife Stadium last week against the Jets. Down a couple of running backs, a starting quarterback, a couple of defensive ends and a star tight end, one has to wonder if San Francisco has enough to pull out a win this Sunday. Add in the players they currently have on injured reserve, and the 49ers appear to be missing nine starters this week.
The Giants have a couple of defensive backs who could miss Sunday's matchup with the 49ers, but the bigger story is that they will be without Saquon Barkley and Sterling Shepard, who were both placed on injured reserve earlier this week.
Rams at Bills (-2)
- Rams: RB Cam Akers (rib) OUT; DB Darious Williams (ankle) QUESTIONABLE
- Bills: RB Zack Moss (toe), TE Dawson Knox (concussion), LB Del'Shawn Phillips (quad) OUT; LB Tremaine Edmunds (shoulder), CB Taron Johnson (groin), LB Matt Milano (hamstring) QUESTIONABLE
Akers left last week's win over the Eagles with the rib injury and did not practice all week, so him being unavailable for this game isn't a surprise. The Rams will counter with more Darrell Henderson and a steady dose of touches for Malcolm Brown in their running back-by-committee approach. Brown didn't practice Wednesday with a finger injury, but he's good to go in this one.
The Bills not having Zack Moss this week is a headline in itself, but they are also a bit banged up on the defensive side of the ball. While Matt Milano finally returned to practice on Friday as a full participant, Tremaine Edmunds was limited all week. Both are listed as questionable for Sunday.
Raiders at Patriots (-5.5)
- Raiders: OT Trent Brown (calf), LB Nick Kwiatkoski (pectoral), WR Henry Ruggs III (knee/hamstring) OUT; RB Josh Jacobs (hip), OG Denzelle Good (thumb/illness) TE Darren Waller (knee), OT Sam Young (groin) QUESTIONABLE
- Patriots: C David Andrews (hand), RB James White (not injury related), LB Josh Uche (foot) OUT; DL Adam Butler (shoulder), WR Julian Edelman (knee), WR N'Keal Harry (ankle), Isaiah Wynn (calf) QUESTIONABLE
After Ruggs decided to give it a go on "Monday Night Football," he will be sitting in Week 3 due to knee and hamstring injuries. Trent Brown will also be out after failing to participate in practice all week due to a calf injury. There remains some questions about Darren Waller and Josh Jacobs' availability, as they are both questionable for Sunday. Both players did return to practice on Friday, but they were limited participants.
White was not with the team all week after a fatal car crash involving his parents in Florida Sunday. Sony Michel and Rex Burkhead will see the majority of the touches in his absence. Andrews is learning to snap left-handed after breaking his thumb, but the Patriots won't give him that opportunity this week. Hjalte Froholdt is the front-runner to start at center. Harry and Edelman were both limited at practice Friday.
Texans at Steelers (-4)
- Steelers: None
- Texans: RB Duke Johnson (ankle), WR Kenny Stills (illness), LB Peter Kalambayi (hamstring) QUESTIONABLE
All Steelers were full participants in practice on Friday, and no one was given an injury designation for Week 3. JuJu Smith-Schuster, who didn't practice on Wednesday and Thursday, was back to work on Friday after dealing with a knee injury. Additionally, defensive end Tyson Alualu (knee contusion) and wide receiver Diontae Johnson (toe) were both full participants for the second straight day.
The Texans are in danger of taking the field without two of their top offensive weapons this Sunday. Johnson was a limited participant all week with an ankle injury while Stills popped up on the injury report on Friday with an illness. He was still able to take part in some of practice, but his status for Week 3 is up in the air.
Bears at Falcons (-3)
- Bears: LB Khalil Mack (knee), DE Mario Edwards Jr. (glute) QUESTIONABLE
- Falcons: S Ricardo Allen (elbow), CB A.J. Terrell (reserve/COVID-19) OUT; WR Julio Jones (hamstring), LB Foyesade Oluokun (hamstring), DE Dante Fowler Jr. (ankle), T Kaleb McGary (knee), DE Takkarist McKinley (groin) QUESTIONABLE
Mack was a limited participant all week with a knee injury while Edwards was a full participant with a glute issue. Wide receivers Anthony Miller (calf), Darnell Mooney (quad) and Allen Robinson (knee) were listed on the injury report but were full participants all week and appear ready for Sunday.
The name to watch for the Falcons is clearly Jones, who didn't practice all week and will be game-time decision. Jones injured his hamstring just before the season and tweaked it again last week's loss to the Cowboys. If Jones can't go, Calvin Ridley and Russell Gage will be relied on heavily by the Falcons in the passing game, which also features tight end Hayden Hurst. Defensively, Atlanta will also be thin, with corners Kendall Sheffield (foot) and A.J. Terrell both ruled out.
Washington at Browns (-7)
- Washington: OT Saahdiq Charles (thigh), LB Cole Holcomb (knee) OUT; WR Steven Sims Jr. (toe), OT Morgan Moses (hip) QUESTIONABLE
- Browns: LB Jacob Phillips (knee), DE Olivier Vernon (abdomen), CB Greedy Williams (shoulder) OUT; DE Adrian Clayborn (hip), LB Mack Wilson (knee), CB Denzel Ward (groin) QUESTIONABLE
Washington will be without linebacker Cole Holcomb again, but it appears veteran Thomas Davis will make his Washington debut after missing the first two games of the season, as will cornerback Kendall Fuller. Two starters on offense could miss Sunday's game, as Sims and Moses are both questionable. However, they both were full participants in practice on Friday.
The Browns are still dealing with several injuries on the defensive side of the ball and could once again be missing some key players in the secondary. While Kevin Johnson is ready to return to the field after suffering a scary liver injury in training camp, Greedy Williams was listed as a limited participant in practice all week and will not play in Week 3. Denzel Ward also appeared to take a step backwards, as he was limited on Thursday but did not practice on Friday. He is listed as questionable.
Titans (-2.5) at Vikings
- Titans: WR A.J. Brown (knee), CB Chris Jackson (hamstring), OLB Derrick Roberson (illness) OUT
- Vikings: CB Cameron Dantzler (rib), CB Mike Hughes (neck), LB Troy Dye (foot) OUT; RB Mike Boone (concussion), CB Kris Boyd (hamstring) QUESTIONABLE
The Titans will be without their star wideout A.J. Brown for the second straight game, but the good news is that cornerback Malcolm Butler will play on Sunday. He has been dealing with a quad injury, and was finally a full participant in practice on Friday.
The key issue with the Vikings entering Sunday is the secondary, as two of their top cornerbacks will be out and another one is questionable. Philip Rivers only threw for 214 yards, one touchdown and one interception against Minnesota last week, but they face a tougher opponent now in Ryan Tannehill.
Jets at Colts (-11.5)
- Jets: WR Jamison Crowder (hamstring), DB Ashtyn Davis (groin), OL George Fant (concussion), WR Breshad Perriman (ankle), DB Quincy Wilson (concussion) OUT; WR Braxton Berrios (hamstring), OL Connor McGovern (hamstring), DB Nate Hairston (hip) QUESTIONABLE
- Colts: CB Rock Ya-Sin (illness), LB Matthew Adams (ankle) OUT; TE Jack Doyle (knee) QUESTIONABLE
The Jets are already banged up heading into Sunday's game and Berrios being added to the injury report Friday doesn't help. New York is already down Crowder, Perriman, and Denzel Mims (injured reserve) at receiver, so potentially losing Berrios isn't ideal for Sam Darnold. Chris Hogan will be getting a lot of targets Sunday. New York is pessimistic McGovern will play and Fant is out, leaving two of its starting offensive lineman unavailable for this one. Again, not ideal for Darnold.
Rock Ya-Sin did not practice all week with an illness, and has already been ruled out for Sunday's matchup. Safety Julian Blackmon was a limited participant all week with a knee injury, but did not have a game designation so it appears he's ready to go.
Panthers at Chargers (-6.5)
- Panthers: OG Dennis Daley (ankle), DT Kawann Short (foot) DOUBTFUL; OT Russell Okung (groin) QUESTIONABLE
- Chargers: QB Tyrod Taylor (ribs/chest), DT Justin Jones (shoulder), LB Asmar Bilal (calf) OUT; LB Nick Vigil (groin), RB Justin Jackson (quadricep), DE Melvin Ingram III (knee) DOUBTFUL; OT Bryan Bulaga (knee), S Rayshawn Jenkins (groin), OG Trai Turner (groin) QUESTIONABLE
The Panthers offensive line is a bit banged up, as it's unlikely Daley will play Sunday while left tackle Okung is questionable. This is especially worrisome since the Chargers have proven they are effective at rushing the passer.
The Chargers likely will be missing a couple of starters on defense, as Melvin Ingram and Nick Vigil are considered doubtful while safety Rayshawn Jenkins is questionable. The offensive line is also a question mark, as both Bryan Bulaga and Trai Turner are questionable.
Cowboys at Seahawks (-5)
- Cowboys: CB Chidobe Awuzie (hamstring) OUT; DE DeMarcus Lawrence (knee), T Tyron Smith (neck) QUESTIONABLE
- Seahawks: DE Rasheem Green (neck) OUT; DE Benson Mayowa (groin), CB Quinton Dunbar (knee), CB Neiko Thorpe (hip), T Cedric Ogbuehi (pectoral) QUESTIONABLE
Cowboys head coach Mike McCarthy said Saturday's practice will be a test to see if Smith can suit up on Sunday, since Dallas didn't practice Friday. Brandon Knight will play left tackle if Smith can't go. Trevon Diggs (shoulder) did not receive an injury designation so he should be good to go for Sunday. Lawrence's status will be determined by Saturday's practice.
The Seahawks placed Green on injured reserve, so he will be out at least three weeks. Seahawks head coach Pete Carroll has indicated Mayowa and Dunbar would be available Sunday, and Dunbar (who didn't practice Friday) would be a huge boost for the cornerback group -- especially with Thorpe being a game-time decision.
Buccaneers (-5.5) at Broncos
- Buccaneers: WR Justin Watson (shoulder) OUT
- Broncos: QB Drew Lock (shoulder), CB Davontae Harris (hamstring) OUT; RB Phillip Lindsay (foot) DOUBTFUL; WR Jerry Jeudy (ribs) QUESTIONABLE
The Buccaneers are mostly healthy going into this one, as Chris Godwin is back after missing Week 2 with a concussion and Scotty Miller (hip) was a full participant in practice Friday. Tom Brady will have his top three wideouts available this week along with a healthy left tackle in Donovan Smith (knee).
The Broncos have been one of the teams that has been crushed by injuries so far this season. Lindsay is in danger of missing his second game in a row due to a foot injury while Jeudy is questionable with a ribs issue. Of course, Lock will miss Sunday's matchup due to the shoulder injury he suffered last week.
Lions at Cardinals (-5.5)
- Lions: TE Hunter Bryant (hamstring), CB Desmond Trufant (hamstring) OUT; WR Kenny Golladay (hamstring), S C.J. Moore (calf), OT Halapoulivaati Vaitai (foot) QUESTIONABLE
- Cardinals: OL Mason Cole (hamstring), WR Christian Kirk (groin) OUT; DL Jordan Phillips (ankle), CB Dre Kirkpatrick (neck) QUESTIONABLE
Golladay missed the first two games for the year for the Lions but is expected to make his season debut Sunday. He was limited in practice all week and will be a huge boost to an offense that has had to relay on Marvin Jones, Danny Amendola and T.J. Hockenson in the passing game. Golladay said he isn't 100% yet, but he's getting there. Trufant was downgraded to out on Saturday.
Kirk failed to recover from a pulled groin in last week's win over Washington and didn't practice all week. Kirk is "week-to-week" which means he could miss some more time going forward. Larry Fitzgerald is in line to see more targets as Arizona, while Andy Isabella will likely see more snaps.
Packers at Saints (-3)
- Packers: WR Davante Adams (hamstring), TE Josiah Deguara (ankle), LB Randy Ramsey (groin) DOUBTFUL; DT Kenny Clark (groin), G Elgton Jenkins (back/rib) QUESTIONABLE
- Saints: WR Michael Thomas (ankle), LB Chase Hansen (hip) OUT; DE Marcus Davenport (elbow), DE Trey Hendrickson (groin), DT David Onyemata (calf) QUESTIONABLE
It looks like the Packers won't have Adams for Sunday's showdown with the Saints, but head coach Matt LaFleur wants to give him the rest of the weekend to see where he's at before ruling him out. Green Bay appears to be playing it safe with Adams, who is third in the league with 17 receptions. If Adams can't go, Marquez Valdes-Scantling and Allen Lazard are the top two wideouts.
The Saints won't have Thomas as he was ruled out for the second consecutive week with an ankle injury, leaving Drew Brees without his No. 1 target once again. Since Thomas is not on injured reserve, there's a chance he returns next week -- but the Saints will rely on Alvin Kamara once again to carry the offense.
Chiefs at Ravens (-3.5)
- Chiefs: DE Alex Okafor (hamstring) OUT; WR Sammy Watkins (concussion/neck), CB Charvarius Ward (hand), FB Dorian O'Daniel (ankle/knee) QUESTIONABLE
- Ravens: CB Tavon Young (knee) OUT; WR Chris Moore (finger), G D.J. Fluker (shoulder), DT Justin Madubuike (knee), LB Anthony Levine (abdomen) QUESTIONABLE
K.C.'s biggest absence could be on the offensive side of the ball, where Watkins has ranked third in targets for Patrick Mahomes. Both Demarcus Robinson and Mecole Hardman would be in line for additional reps outside in the event he's unable to go. Ward, meanwhile, would likely be replaced by Rashad Fenton or Antonio Hamilton at corner.
The Ravens could be missing some key depth pieces on the defensive side of the ball, with Young already ruled out and two other players questionable. Justice Hill is good to go after a week of full practices, though it remains to be seen how he'll mix in to the running back rotation.