The Fresno State Bulldogs look to continue their remarkable second half turnaround as they close out the regular season against Mountain West rival, the Wyoming Cowboys on Friday night. Fresno State, 7-4, has won six straight games after defeating Nevada, 41-14 in Reno last Saturday. They will face Boise State in the conference championship game next Saturday. Wyoming, also 7-4, lost a close one at home to Boise State, 20-17. Last year, the Bulldogs shut out the Cowboys, 17-0 in Laramie. Wyoming is 6-4 against the spread, while Fresno State is 4-6 ATS in 2022.

Kickoff is scheduled for 10 p.m. ET at Bulldog Stadium. The Bulldogs are favored by 15 points in the latest Fresno State vs. Wyoming odds from Caesars Sportsbook, and the over/under is set at 50.5. Before entering any Wyoming vs. Fresno State picks, you'll want to see the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Fresno State vs. Wyoming and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds and betting lines for Wyoming vs. Fresno State:

  • Wyoming vs. Fresno State spread: Fresno State -15
  • Wyoming vs. Fresno State over/under: 50.5 points
  • Wyoming vs. Fresno State money line: Fresno State -650, Wyoming +460
  • Wyoming vs. Fresno State picks: See picks here
Latest Odds: Fresno State Bulldogs -14

What you need to know about Wyoming

The Cowboys' four game winning streak was snapped in their home finale against the Mountain West leaders, Boise State. Surprisingly the game was close although the Broncos dominated the time of possession, 36:29 to 23:31 and Wyoming only ran 48 plays as compared to Boise State's 77. Junior running back Titus Swen was the star on Saturday, rushing 19 times for 212 yards and a score. He leads the team with 964 yards and eight rushing touchdowns on 183 carries.

Wyoming has the seventh least proficient passing attack among FBS schools, averaging only 129.9 yards per game through the air. Starting quarterback Andrew Peasley missed the Boise State game due to a concussion and his backup, Jayden Clemons was not effective at all against the Broncos. Clemons completed only three of 16 passes for 30 yards and three interceptions, helping to seal the Cowboys' fate. It's unclear as to whether Peasley will be healthy enough to return this Friday against Fresno State.

What you need to know about Fresno State

The Bulldogs opened 1-4 and the season seemed to be going nowhere after star QB Jake Haener was injured in a blowout loss to USC. But Fresno State has reeled off six straight wins and gets the chance next Saturday to win its first conference championship since 2018. Since returning at the end of October, Haener's play has been brilliant. He's thrown for 1,395 yards and 12 touchdowns in those four games, while only throwing two interceptions. Haener added two touchdown runs in last week's win over Nevada. Even more impressively, the Fresno State senior QB is completing nearly 75 percent of his passes on the season and is building himself quite the tape for NFL scouts.

In last week's blowout victory over Nevada, running back Jordan Mims rushed 19 times for 156 yards and a touchdown. That performance put him over the 1,000 yard rushing mark for the first time in his Bulldogs career. Mims has also accounted for 12 touchdowns including 11 on the ground. Senior WR Jalen Moreno-Cropper topped the 100 yard receiving mark for the second straight game, catching seven passes for 136 yards against Nevada. He leads the team in 2022 with 72 catches for 971 yards and five scores.

How to make Wyoming vs. Fresno State picks

The model has simulated Wyoming vs. Fresno State 10,000 times and the results are in. The model is leaning Over on the point total, and it's also generated a point-spread pick that is hitting in nearly 60% of simulations. You can only see the pick at SportsLine.

So who wins the Wyoming vs. Fresno State matchup? And which side of the spread hits nearly 60% of the time? Visit SportsLine now to see which side of the Fresno State vs. Wyoming spread to jump on, all from the advanced model that finished the past six-plus years up almost $3,000 on its FBS college football picks, and find out.