The Cincinnati Bearcats (2-2) and the BYU Cougars (3-1) will meet on Friday night in a Big 12 showdown between conference newcomers. This will only be the third game in history between these schools. Cincinnati ranks seventh in the Big 12 in scoring (30.8). BYU is right behind the Bearcats in the eighth spot with 30 points per game. 

The BYU vs. Cincinnati start time is 10:15 p.m. ET. The Cougars are 1-point favorites in the latest Cincinnati vs. BYU odds, while the over/under for total points is 49. Before making any BYU vs. Cincinnati picks, be sure to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Cincinnati vs. BYU and just revealed its picks and predictions. You can visit SportsLine now to see the model's picks. Here are several college football odds and trends for BYU vs. Cincinnati:

  • Cincinnati vs. BYU spread: BYU -1
  • Cincinnati vs. BYU over/under: 49 points
  • Cincinnati vs. BYU money line: Bearcats -114, Cougars -106
  • CIN: Cincinnati has hit the team total Under in its last four games
  • BYU: BYU has hit the 1H game total Over in eight of its last 12 games
  • Cincinnati vs. BYU picks: See picks at SportsLine
  • Cincinnati vs. BYU live stream: fubo (try for free)

Why Cincinnati can cover

The Bearcats bring an aggressive defensive unit into this matchup. Through four games, Cincinnati has totaled 12 sacks and ranks seventh in the Big 12 in total defense (336.8). Senior linebacker Dorian Jones has been thriving at the second level of the defense. Jones is leading the team in total tackles (26). In his last game, the Louisville transfer had a season-high 13 tackles and one sack.

Junior safety Bryon Threats provides Cincinnati with an athletic defender in the secondary. Threats is a reliable tackler in the run game with terrific instincts in coverage. The Ohio native is third on the team in total tackles (19), second in pass breakups (3) and first in interceptions (2). This unit has given more than 21 points just one time this season. See which team to pick here.

Why BYU can cover

Senior quarterback Kedon Slovis is leading the Cougars offense. The Pittsburgh transfer owns the composure and poise to stay calm under center. The Arizona native has thrown for 1,017 yards and eight passing touchdowns. In his last contest against Kansas, Slovis had 357 yards and two passing scores.

The Cougars have had three players log at least 200 receiving yards. Junior tight end Isaac Rex consistently gets open and excels as a blocker. Rex leads the team in receiving yards (260) with 17 receptions and one score. Sophomore receiver Chase Roberts has been another effective pass-catcher. Roberts has snagged at least five catches in three of his last four games. The Utah native caught 18 balls for 227 yards and two touchdowns. Last week, he had five grabs for 89 yards. See which team to pick here

How to make BYU vs. Cincinnati picks

SportsLine's model is leaning Over on the point total, projecting the teams to combine for 50 points. The model also says one side of the spread hits in well over 60% of simulations. You can only see the model's picks at SportsLine.

So who wins Cincinnati vs. BYU, and which side of the spread hits in well over 60% of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced computer model that's up more than $2,500 on its top-rated college football spread picks since its inception, and find out.