Offensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Quarterback | Z. WilsonZach Wilson | T. BoyleTim Boyle | |
| Running Back | B. HallBreece Hall | D. CookDalvin Cook | |
| Fullback | N. BawdenNick Bawden | — | — |
| Wide Receiver | G. WilsonGarrett Wilson | A. LazardAllen Lazard | |
| Tight End | T. ConklinTyler Conklin | C. UzomahC.J. Uzomah | |
| Left Tackle | D. BrownDuane Brown | B. TurnerBilly Turner | — |
| Left Guard | L. TomlinsonLaken Tomlinson | W. SchweitzerWes Schweitzer | — |
| Center | C. McGovernConnor McGovern | J. TippmannJoe Tippmann | — |
| Right Guard | A. Vera-TuckerAlijah Vera-Tucker | — | — |
| Right Tackle | M. BectonMekhi Becton | M. MitchellMax Mitchell | — |
Defensive Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Left Defensive End | J. Franklin-MyersJohn Franklin-Myers | B. HuffBryce Huff | |
| Right Defensive End | J. Johnson IIJermaine Johnson II | C. LawsonCarl Lawson | |
| Left Defensive Tackle | Q. JeffersonQuinton Jefferson | S. ThomasSolomon Thomas | — |
| Right Defensive Tackle | Q. WilliamsQuinnen Williams | — | — |
| Strongside Linebacker | Q. WilliamsQuincy Williams | — | — |
| Middle Linebacker | C. MosleyC.J. Mosley | C. SurrattChazz Surratt | |
| Weakside Linebacker | J. SherwoodJamien Sherwood | Z. BarnesZaire Barnes | — |
| Right Cornerback | D. ReedD.J. Reed | B. EcholsBrandin Echols | |
| Left Cornerback | S. GardnerSauce Gardner | M. Carter IIMichael Carter II | |
| Strong Safety | J. WhiteheadJordan Whitehead | A. DavisAshtyn Davis | |
| Free Safety | T. AdamsTony Adams | A. AmosAdrian Amos | — |
Special Teams Positions
| POS | Starter | Second | Third+ |
|---|---|---|---|
| Punter | T. MorsteadThomas Morstead | — | — |
| Kicker | G. ZuerleinGreg Zuerlein | — | — |
| Long Snapper | T. HennessyThomas Hennessy | — | — |
| Holder | T. MorsteadThomas Morstead | — | — |
| Punt Returner | X. GipsonXavier Gipson | M. HardmanMecole Hardman | — |
| Kick Returner | X. GipsonXavier Gipson | M. HardmanMecole Hardman | — |