The second-ranked Michigan Wolverines hit the road for the first time this season and will face a tough crowd at Memorial Stadium on Saturday when they meet the Nebraska Cornhuskers. The Wolverines (4-0) have eased into the season with four victories against overmatched foes. They enter this college football week 5 matchup off a 31-7 victory against Rutgers last Saturday. The Cornhuskers (2-2) beat Louisiana Tech 28-14 at home the same day for a second straight victory. Nebraska could be gaining steam under new coach Matt Rhule, but the Wolverines have beaten the Huskers in the past three meetings. UM won 34-7 in Ann Arbor last November.

Kickoff is set for 3:30 p.m. ET in Lincoln, Neb. The Wolverines are listed as 17.5-point favorites in the latest Michigan vs. Nebraska odds list. The over/under for total points scored is 39.5. Before locking in any Nebraska vs. Michigan picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of nearly $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Michigan vs. Nebraska and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for Nebraska vs. Michigan: 

  • Michigan vs. Nebraska spread: Wolverines -17.5
  • Michigan vs. Nebraska over/under: 39.5 points
  • Michigan vs. Nebraska money line: Wolverines -1043, Cornhuskers +654
  • MICH: The Wolverines are 6-2-1 ATS in conference games since 2022.
  • NEB: The Huskers are 6-4 ATS in its past 10 Big Ten matchups.
  • Michigan vs. Nebraska picks: See picks at SportsLine 
  • Michigan vs. Nebraska live stream: fubo (try for free)

Why Michigan can cover

Michigan hasn't been tested yet, and it might not be Saturday, either. The Cornhuskers have one of the nation's worst passing offenses, averaging just 124.5 yards per game (123rd in FBS). The Wolverines lead the nation in total yards allowed (231.5), giving up just 151 through the air (fifth). Opposing rushers are gaining 2.8 yards per carry (13th). UM also is the national leader in scoring defense, yielding 5.8 per game. It has outscored opponents by an average of 26 points.

The Huskers are just plus-3 in point differential, and they have turned the ball over nine times. Michigan's offense will be the first real test of Nebraska's run defense, and Blake Corum is averaging 6.1 yards per rush. He also has 26 rushing TDs since the start of last season, by far the most in the nation. Quarterback J.J. McCarthy leads the nation in completion percentage, and receiver Roman Wilson averages 17.9 yards per catch and has scored six touchdowns. See which team to pick here.

Why Nebraska can cover

Nebraska has been playing smothering defense, especially against the run. The Huskers are allowing 4.2 yards per play (12th in FBS) and a paltry 1.8 yards per rush (second). Opponents are scoring 18.5 points per game (28th), but only Colorado scored more than 14, and NU turnovers created a lot of extra chances. Nebraska turned the ball over eight times in the first two games but just once over its two victories.

The last meeting between these teams in Lincoln finished 32-29 in favor of the Wolverines. The Memorial Stadium crowd will be tough on UM's offense. Rhule also will have his team believing it can pull off the upset. The former Carolina Panthers coach had success at Temple and Baylor and is expected to do the same here. The Huskers have rushed for 526 yards over their two victories, 255 from quarterback Heinrich Haarberg, starting in place of the injured Jeff Sims. See which team to pick here.

How to make Michigan vs. Nebraska picks

SportsLine's model is leaning Over on the total, projecting the teams to combine for 46 points. The model also says one side of the spread is the better value. You can only see the model's pick at SportsLine

So who wins Nebraska vs. Michigan, and which side of the spread is the better value? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of almost $2,500 on its top-rated college football spread picks, and find out.