The Arkansas Razorbacks and Missouri Tigers close out their regular season against each other when they collide in the Battle Line Rivalry on Friday at Faurot Field in Columbia, Mo. The Razorbacks (6-5, 3-4 in SEC) are looking to win in Columbia for the first time in program history. They are winless in five games against Missouri in Columbia. Meanwhile the Tigers (5-6, 2-5) need a victory on Friday to become bowl-eligible for the third straight season. The last time the program went to three straight bowl games came when they went to seven straight postseason games between 2006-11. 

Kickoff is 3:30 p.m. ET. The Razorbacks are 3.5-point favorites in the latest Arkansas vs. Missouri odds from Caesars Sportsbook, while the over/under for total points scored is 55.5. Before locking in any Missouri vs. Arkansas picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed the model has seen huge returns.

Now the model has dialed in on Arkansas vs. Missouri and just revealed its coveted picks and predictions. You can head to SportsLine now to see all of the model's college football picks. Now, here are the college football odds and trends for Missouri vs. Arkansas:  

  • Arkansas vs. Missouri spread: Razorbacks -3.5
  • Arkansas vs. Missouri over/under: 55.5 points 
  • Arkansas vs. Missouri money line: Razorbacks -170, Tigers +143 
  • ARK: The Razorbacks rank eighth in the country in rushing yards per game (233.5) 
  • MIZ: The Tigers average 7.2 tackles for loss per game, which leads the conference 
  • Arkansas vs. Missouri picks: See picks here
  • Arkansas vs. Missouri streaming: Paramount+
Featured Game | Missouri Tigers vs. Arkansas Razorbacks

Why the Razorbacks can cover

Arkansas has one of the top defensive players in the country in linebacker Drew Sanders. A transfer from Alabama, Sanders is tied for third in the country in forced fumbles (11) and is 13th in sacks (8.5). He also has made 96 tackles with a team-leading 12.5 tackles for loss. For his efforts this season he has been named a finalist for the Butkus Award, which goes to the nation's best linebacker.

In addition, the Razorbacks have one of the best ground games in the FBS. Arkansas is averaging 233.5 rushing yards per game, which ranks second in the SEC and eighth nationally. The team also has rushed for 200 yards in an SEC-leading eight games this season.

Why the Tigers can cover

Missouri appears to have a big edge on special teams with punt returner Luther Burden III facing Arkansas' punt return defense. A 5-foot-11 freshman from St. Louis, Burden is tied for fifth in the country in punt return touchdowns (one) and is averaging 13.7 yards per return. He faces a Razorbacks special teams unit that ranks a woeful 124th in the nation in punt return defense (14.4 yards per return).

In addition, the Tigers have a playmaker in the defensive backfield in Kris Abrams-Draine. A 5-foot-11 junior from Mobile, Ala., Abrams-Draine ranks second in the FBS and 11th in the country in passes defended per game (1.3). Last week against New Mexico State he had two pass breakups and six tackles. 

How to make Arkansas vs. Missouri picks

SportsLine's model is leaning Under on the point total, projecting the teams to combine for 53 points. It also has an against-the-spread pick that cashes in almost 60% of simulations. You can see the model's Missouri vs. Arkansas pick only at SportsLine.

So who wins Arkansas vs. Missouri? And which side is covering almost 60% of the time? Visit SportsLine now to see which side of the Missouri vs. Arkansas spread to jump on, all from the advanced model that is up almost $3,000 on top-rated picks over the past six years, and find out, and don't forget to stream on Paramount+.