The San Francisco 49ers will attempt to prove why they had the top defense in the NFL during the regular season when they visit the Philadelphia Eagles on Sunday in the 2023 NFC Championship Game. San Francisco (15-4) ranked first in yards allowed (300.6) and also led the league in points allowed (16.3), but has yielded more than those averages (307, 17.5) in the 2023 NFL playoffs thus far. The 49ers will face one of the NFL's top offensive teams, the Philadelphia Eagles (15-3), who ranked third in yardage (389.1) and points (28.1) in 2022.

Kickoff is 3 p.m. ET. Philadelphia is a 2.5-point favorite in the latest 49ers vs. Eagles odds from Caesars Sportsbook, and the over/under for total points scored is 45.5. Before you make any Eagles vs. 49ers picks or NFC Championship Game predictions, you need to see which side Vegas legend and 49ers expert Micah Roberts is on

Roberts worked in the Las Vegas sportsbook industry for more than 20 years, including a 13-year run as Station Casinos' book director. Armed with an elaborate network of sources, Roberts has unmatched info in multiple sports.

He also has been uncanny with his picks in games involving the 49ers. In fact, he is 16-5 on his last 21 against-the-spread picks involving San Francisco. Anyone who has followed him is way up.

Now, Roberts has zeroed in on Eagles vs. 49ers and locked in his NFC Championship Game picks and predictions. You can head to SportsLine now to see his picks. Now, here are several NFL odds and betting lines for 49ers vs. Eagles:

  • 49ers vs. Eagles spread: Philadelphia -2.5 
  • 49ers vs. Eagles over/under: 45.5 points 
  • 49ers vs. Eagles money line: Philadelphia -145, San Francisco +122 
  • PHI: The led the NFL in pass defense during the regular season 
  • SF: 49ers led the league in the regular season in scoring defense (16.3 points per game) 
  • 49ers vs. Eagles picks: See picks here
Featured Game | Philadelphia Eagles vs. San Francisco 49ers

Why the Eagles can cover

It's difficult to beat a division-rival three times in a single season, but the Eagles didn't bat an eyelash at the Giants in their third matchup of the season last week. Philadelphia rolled to a 38-7 victory in which it simply overpowered its division foe. The Eagles rushed 44 times for 268 yards and outgained the Giants by a 189 yards.

Kenneth Gainwell ran for 112 yards and a score, while Miles Sanders also rushed for 90 yards. Jalen Hurts and Boston Scott also contributed rushing touchdowns and each topped the 30-yard mark. Philadelphia is 15-1 on the season when Hurts has started and even with Brock Purdy playing well in his rookie season, the Eagles have to feel like they have the quarterback advantage entering Sunday. See which team to pick here.

Why the 49ers can cover

The 49ers excelled at creating turnovers during the regular season and also have done well in the NFL playoffs 2023. San Francisco led the NFL with a plus-13 turnover differential while tying for first with 20 interceptions and second with 30 overall takeaways. In its two postseason contests, the team has four takeaways and three interceptions, ranking second in both categories.

Tashuan Gipson was tied for fifth in the league with five interceptions, his highest total since recording a career-best six in 2014 with Cleveland, while fellow safety Talanoa Hufanga made four picks in his second NFL season. Cornerback Deommodore Lenoir, who also is in his second year in the league, has registered a pair of interceptions in the NFL playoffs after having just one over 17 regular-season games. Defensive end Nick Bosa has been a nightmare for opposing quarterbacks in 2022 as he has 95 pressures, including playoffs, and was the league leader with 18.5 sacks in the regular season. See which team to pick here.

How to make 49ers vs. Eagles picks

Now, Roberts has broken down Eagles vs. 49ers from every angle. We can tell you that he's leaning Over the point total, but his much stronger play is on the spread. He's found a critical x-factor that makes one side of the spread hit hard. He's sharing what it is, and which side to back, only at SportsLine.

So who wins Eagles vs. 49ers in the NFC Championship Game 2023? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine now to see which side of the Eagles vs. 49ers spread you should jump on Sunday, all from the former Vegas bookmaker who is 16-5 on picks involving the 49ers, and find out.