Men's singles players who have combined to win 11 tournaments in 2023, including one Grand Slam, meet when top-ranked Carlos Alcaraz of Spain battles third-ranked Daniil Medvedev of Russia at the 2023 U.S. Open semifinals on Friday. It will be the fourth all-time meeting between the two and third this year. Alcaraz has won both encounters in 2023 to hold a 2-1 edge. Alcaraz earned a 6-3, 6-3, 6-3 victory over Medvedev at Wimbledon this past July.

This U.S. Open 2023 semifinal is schedule for 7 p.m. ET at Arthur Ashe Stadium in Flushing Meadows, N.Y. Alcaraz is listed as the -425 favorite (risk $425 to win $100) on the money line, while Medvedev is at +290. The over/under for total games is 35.5, with Alcaraz favored by 5.5 games. Before making any Alcaraz vs. Medvedev picks or 2023 U.S. Open predictions, you need to see what tennis expert Jose Onorato has to say.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players. Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bet. 

He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach has helped Onorato go 128-90-7 (+69.25 units) since 2022.

Now, Onorato has scrutinized the latest U.S. Open 2023 odds and released his coveted best bet for the Alcaraz vs. Medvedev semifinal match. He's sharing his pick and analysis only at SportsLine.

Carlos Alcaraz vs. Daniil Medvedev preview

Onorato sees both players as being capable of raising the trophy. The 20-year-old Alcaraz has been dominant since turning pro in 2018 and is making his fourth semifinal appearance in a Grand Slam. Besides winning at New York last year, he is coming off this year's Wimbledon championship. He also reached the semifinals of the 2023 French Open.

Alcaraz is coming off a 5-7, 7-6 (7), 7-6 (4) loss to second-ranked Novak Djokovic of Serbia in the finals of a tune-up tournament in Cincinnati last month. Alcaraz has won six tournaments and finished second in two others this year. He also reached the semifinals in three events, as well as the quarterfinals in another. For his career, he has compiled a record of 226-57 (79.9%).

The 27-year-old Medvedev has also had lots of success this year. Not only has he recorded five tournament championships, he has reached the finals once, the semifinals three times and the quarterfinals three times. He has been dominant in New York, having been tested in just two events and both of those went just four sets. He advanced to the semifinals with a 6-4, 6-3, 6-4 win over Russian Andrey Rublev on Wednesday.

The only other match to go four sets was in the second round when Medvedev defeated Australian Christopher O'Connell 6-2, 6-2, 6-7 (6), 6-2. Since turning pro in 2014, Medvedev has earned 20 singles titles and reached a Grand Slam finals four times, winning the U.S. Open two years ago. For his career, he has compiled a 478-191 (71.4%) overall record, including 213-67 (76.1%) on hard surfaces. This year, he has gone 54-11 (83.1%) overall. See who Onorato is backing right here.

How to make Alcaraz vs. Medvedev picks

In addition to a full breakdown of the match, Onorato has released a pair of strong best bets, including one that returns almost +300. Be sure to see Onorato's pick and analysis before locking in your 2023 U.S. Open picks.

What are the best bets for Medvedev vs. Alcaraz in the semifinals of the 2023 U.S. Open? Visit SportsLine now to see Jose Onorato's best bets, all from the tennis expert who's up nearly 70 units since 2022, and find out.