Panama's last World Cup appearance was also its first in 2018, but it ended in disappointment without a single win in the group stage. Los Canaleros would relish a second chance to do better than their last showing, but with a dwindling number of Concacaf 2022 World Cup qualifying matches remaining, they need a positive result against Mexico on Wednesday. A win could push Panama as high as second in the table. You can see what happens when you stream all the action on Paramount+.

Kickoff is set for 10 p.m. ET. Caesars Sportsbook lists Mexico as the -345 favorite (risk $345 to win $100) on the 90-minute money line in its latest Mexico vs. Panama odds, while Panama is a +900 underdog. A draw is priced at +340 and the over-under for total goals scored is 2.5. Wednesday's showdown will be streamed live on Paramount+ with their must-have Premium plan.

Paramount+ now has levels of membership so you can watch the World Cup Qualifiers and much more. The Premium Plan is $9.99 per month and you can watch your local CBS live stream (including plenty of sports like SEC on CBS, NFL on CBS, and the PGA Tour), no ads, on demand and the ability to download episodes for offline viewing. Both plans come with a free week to start, so sign up now here.

How to watch Mexico vs. Panama

  • Mexico vs. Panama date: Wednesday, February 2
  • Mexico vs. Panama time: 10 p.m. ET
  • Mexico vs. Panama live stream: Paramount+

Concacaf World Cup qualifying picks for Panama vs. Mexico

Before you tune in to Wednesday's World Cup qualifiers, you need to see the Mexico vs. Costa Rica picks from soccer insider Martin Green. After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Since then, his European soccer picks have been spot-on. Green has generated over $37,000 for $100 bettors since the 2017-18 season, and he has his finger on the pulse of the game all over the globe.

For Panama vs. Mexico, Green is backing Panama to stay within the 1.5-goal spread. Even though Panama is a heavy underdog, it has an opportunity to make a move up the Concacaf standings with a win. Additionally, Los Canaleros should feel that it is the side coming in with momentum after its recent run of strong play.

The discouraging trend for Mexico over its last four games is that El Tri has won the possession battle in each match and outshot each of their opponents except for the USMNT, yet has taken just one win, a draw and two losses from those fixtures. If Panama can limit its mistakes, it might not win, but both teams' recent form suggests Los Canaleros can stay within two goals of Mexico.

"Costa Rica is a difficult team to play against, as it defends deep and rarely displays much attacking ambition," Green told SportsLine. "The Mexican forwards should improve against Panama, but it is hard to justify betting on El Tri to cover a 1.5-goal handicap spread."

How to watch, live stream World Cup qualifiers on Paramount+

Now that you know what to pick, get ready to watch the Concacaf World Cup qualifiers. Visit Paramount+ now to see the World Cup Qualifiers, your live local CBS sporting events, some of the world's top soccer matchups and much more