Nineteenth-ranked Iowa State looks to get back on track when it hosts Oklahoma on Monday. The Cyclones (19-8, 8-6) have lost two in a row and three of four, while the Sooners (17-10, 5-9) have won two straight. Both are looking to finish the regular season strong as they try to improve their position in the NCAA Tournament bracket. Tipoff from Hilton Coliseum is set for 8 p.m. ET. Iowa State is fifth in the Big 12, three games behind first place Kansas State and one behind third place Kansas and Baylor. The Cyclones are favored by nine points in the latest Oklahoma vs. Iowa State odds, while the over-under for total points scored is 143. Before making any Oklahoma vs. Iowa State picks of your own, be sure to check out the college basketball predictions from SportsLine's proven model. 

This model, which simulates every game 10,000 times, has raked in the winnings for those following its picks. Over the past two years, the SportsLine Projection Model has returned over $5,200 to $100 players on its top-rated college basketball picks. It also entered Week 16 of the 2018-19 college basketball season on a blistering 16-8 run on top-rated college basketball side picks either against the spread or on the money line. Anyone who has followed it is way up. 

Now the model has dialed in on Oklahoma vs. Iowa State. We can tell you it's leaning over, and it has a strong against-the-spread pick that cashes in well over 50 percent of simulations. That one is only available at SportsLine.

The model knows that despite their recent struggles, the Cyclones have won seven of 11, including a 75-74 win at Oklahoma. Iowa State is 11-3 at home and is looking for its seventh NCAA Tournament appearance in eight seasons. The Cyclones have won four of the past five meetings with the Sooners and 12 of 18 since the 2011-12 season. Iowa State has won three of the past five Big 12 Conference Tournament titles as well.

Senior guard Marial Shayok (18.5 ppg) has come up big when needed, scoring 24 points vs. Texas Christian and 26 at Kansas. Sophomore guard Lindell Wigginton (13.2 ppg) has surpassed his average in six of 10, including 28 versus West Virginia and 23 at Kansas State.

But just because the Cyclones come in hot doesn't guarantee they will cover the Oklahoma vs. Iowa State spread. 

The model also knows Oklahoma is eighth in the conference, but has had a winning record in six of the past seven seasons. The Sooners have qualified for the NCAA Tournament in five of the past six years and are 5-5 on the road. Oklahoma enters with an edge in rebounding: The Sooners are 35th in the nation (38.7 rpg), compared to Iowa State, which is 192nd (35.3).

Senior guard Christian James (15.5 ppg) has led Oklahoma, scoring 19 points against Texas on Saturday and 21 vs. Vanderbilt. Also red hot is sophomore forward Brady Manek (11.7 ppg), who has equaled or surpassed his average in eight of the past 10, including 18 at West Virginia. Junior forward Kristian Doolittle (10.1 ppg) has equaled or surpassed his average in five of seven, including 21 at TCU and 19 against Iowa State.

So who wins Iowa State vs. Oklahoma? And which side of the spread can you bank on in well over 50 percent of simulations? Visit SportsLine now to see which side of the Iowa State vs. Oklahoma State spread to jump on, all from the advanced model that is up more than $5,200 on its college basketball picks the past two years, and find out.