If you're a soccer fan, Saturday's MLS schedule is exactly what you're looking for. Fourteen matches are set to be played, beginning with seven games at 7:30 p.m. ET. The action wraps up with four games at 10:30 p.m., including Lionel Messi and Inter Miami traveling north of the border to take on the Vancouver Whitecaps. Messi's stellar play has Inter Miami sitting on top of the Eastern Conference standings with 31 points. The Herons are the slight +145 favorites (risk $100 to win $145) in the latest MLS odds, while the Whitecaps are +155 underdogs.

Will Messi lead Inter Miami to another win on the road, or should your MLS best bets involve a matchup like Atlanta United vs. LAFC, New England Revolution vs. NYCFC, or D.C. United vs. Chicago Fire? Before entering any MLS picks for Saturday, May 25, be sure to see the MLS betting advice and score projections from SportsLine's soccer expert Brandt Sutton

Sutton, a former collegiate soccer player, has been SportsLine's top soccer editor for more than six years. He has followed soccer closely for much longer and factors in managerial tactics, projected lineups and past performances to make the most-informed decisions possible, keeping his finger on the pulse of the game all over the globe.

Sutton finished 2022 as SportsLine's top soccer expert with a 165-130-2 mark, returning nearly $2,200 for $100 players. He was also profitable across multiple leagues in 2023, including the English Premier League, UEFA Champions League, FA Cup, Europa League, and more. 

Now, Sutton has analyzed the full MLS schedule for Saturday, May 25, and locked in his exact score projections and MLS best bets. You can head to SportsLine now to see Sutton's picks

Top MLS predictions for Saturday, May 25

One of Sutton's MLS score predictions is that Messi leads Inter Miami (+145) to a comfortable 3-1 victory on the road against the Vancouver Whitecaps. Inter Miami are extremely efficient in the attacking third, having scored 36 goals through 15 games this season. The Herons have scored nine more goals than the next-closest team (Real Salt Lake) and they've been firing on all cylinders on the road.

Inter Miami have scored three or more goals in four of their last six games away from home thanks to the brilliance of Messi and Luis Suarez. Messi has racked up 10 goals and 12 assists this season, while Suarez has found the back of the net 11 times in 2024.

The Whitecaps, meanwhile, have struggled to get results at home, winning just two of their six league games at BC Place. Vancouver is also winless in its last five matches in MLS play, scoring just two goals during that stretch. See the rest of Sutton's MLS score predictions here

How to get MLS picks, score predictions, best bets  

Sutton has locked in his exact score projections for every MLS match on Saturday, as well as his three most confident best bets. They include an underdog winning outright on the road and a high-scoring slugfest between two of the league's top teams. You can only see MLS score predictions and best bets at SportsLine.  

So which MLS picks can you make with confidence, and which underdog will pull off a shocking upset? Check out the latest MLS odds below, then visit SportsLine to see exact NFL score predictions for Saturday, May 25, all from the insider who has constantly crushed his soccer picks

MLS odds, schedule for Saturday, May 25 (all times p.m. ET)

Orlando City vs. Columbus Crew (7:30)
Orlando -110, Draw +260, Columbus +260

Atlanta United vs. LAFC (7:30)
ATL +145, Draw +260, LAFC +160

CF Montreal vs. Nashville SC (7:30)
Montreal +140, Draw +230, Nashville +180

New England Revolution vs. NYCFC (7:30)
New England +145, Draw +250, NYCFC +160

Charlotte FC vs. Philadelphia Union (7:30)
Charlotte +130, Draw +240, Philadelphia +190

Toronto FC vs. FC Cincinnati (7:30)
Cincinnati +130, Draw +240, Toronto +190

DC United vs. Chicago Fire (7:30)
DC -140, Draw +300, Chicago +320

St. Louis vs. Seattle Sounders (8:30)
St. Louis +125, Draw +230, Seattle +200

FC Dallas vs. Real Salt Lake (8:30)
Salt Lake +140, Draw +230, Dallas +180

Colorado Rapids vs. Minnesota United (9:30)
Colorado -115, Draw +280, Minnesota +260

Portland Timbers vs. Sporting KC (10:30)
Portland -115, Draw +280, Kansas City +260

San Jose Earthquakes vs. Austin FC (10:30)
San Jose -125, Draw +280, Austin +300

Vancouver Whitecaps vs. Inter Miami (10:30)
Miami +145, Draw +270, Vancouver +155

LA Galaxy vs. Houston Dynamo (10:30)
LA -125, Draw +280, Houston +300