Marner gave Toronto a 4-0 lead with his 11th goal of the season, scoring on a slap shot after a Los Angeles turnover inside its blue line.
''It's a nice clap bomb he has there,'' Maple Leafs center Auston Matthews said. ''I didn't know he could shoot the puck like that.''
Marner became the 10th player in the past 35 years to string together a streak of 21 or more games. He has 10 goals and 16 assists during the run.
Matthews, Pierre Engvall, David Kampf and William Nylander also scored for Toronto. Ilya Samsonov made 29 saves for his first shutout with the Maple Leafs and the seventh of his career.
''Thank you, video coaches,'' Samsonov said.
Toronto has won seven of eight to improve to 17-5-6.
Los Angeles dropped to 14-11-4 with its seventh loss in 10 games. Kings goalie Jonathan Quick made 36 saves.
Kings: At Montreal on Saturday night.
Maple Leafs: Host Calgary on Saturday night.
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