The Cincinnati Bengals will meet the Los Angeles Rams in an interconference matchup on Monday Night Football. The Bengals (0-2) are off to a slow start for the second year in a row and are coming off a 27-24 loss to the Baltimore Ravens in Week 2 as quarterback Joe Burrow nurses a calf injury and is questionable. The Rams (1-1) are looking to get back into the win column after dropping a 30-23 decision to the San Francisco 49ers last Sunday. Cincinnati leads the all-time regular-season series 8-6, including wins in three of the past four meetings. 

Kickoff is set for 8:15 p.m. ET. The Bengals are two-point favorites in the latest Rams vs. Bengals odds, while the over/under for total points scored is 43.5. Before making any Bengals vs. Rams picks, be sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2023 NFL season on an incredible 164-117 run on top-rated NFL picks that dates back to the 2017 season. It is also on an 18-9 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Rams vs. Bengals and just locked in its picks and predictions. You can visit SportsLine now to see the model's picks. Here are the NFL odds and betting lines for Rams vs. Bengals:

  • Rams vs. Bengals spread: Bengals -2
  • Rams vs. Bengals over/under: 43.5 points 
  • Rams vs. Bengals money line: Los Angeles Rams +120, Cincinnati -140 
  • LAR: Rams are 2-0 against the spread so far this season 
  • CIN: Bengals have not had a losing record since 2020 
  • Rams vs. Bengals picks: See picks at SportsLine 
  • Rams vs. Bengals live stream: fubo (try for free)

Why the Bengals can cover

Wide receiver Tee Higgins led Cincinnati with eight catches for 89 yards and two touchdowns in the loss to the Baltimore Ravens last week, his third career game with two receiving touchdowns. In his last meeting against the Los Angeles Rams, he had four catches for 100 yards and two touchdowns in Super Bowl LVI. Higgins also has a touchdown catch in two of his past three games in primetime, including in his last game on Monday Night Football (Oct. 31, 2022, at Cleveland).

Also helping power the offense as quarterback Joe Burrow tries to recover from a calf injury is wide receiver Tyler Boyd. He had six catches for 52 yards in the Week 2 loss to the Ravens. He has five or more catches in each of two career games against the Rams, including Super Bowl LVI. For the season, Boyd has eight receptions for 62 yards (7.8 average), including a long of 13 yards. He is in his eighth season with Cincinnati and in 105 games, has 454 catches for 5,395 yards (11.9 average) and 29 touchdowns. See which team to pick here.

Why the Rams can cover 

Rookie wide receiver Puka Nacua (questionable) is off to a fast start to his career. The fifth-round draft choice in the 2023 NFL Draft has caught 25 passes for 266 yards (10.6 average). He has had three explosive plays of 20 or more yards, and has converted 13 first downs. Nacua is coming off a 15-catch, 147-yard effort in the loss to San Francisco.

Defensively, the Rams are led by veteran defensive tackle Aaron Donald. Donald has four tackles, including two solo, with one half-sack for four yards. He is in his 10th season with the Rams, and has played in 140 career games. He has registered 493 tackles, including 311 solo, with 103.5 sacks, 24 forced fumbles, seven fumble recoveries and 18 pass breakups. See which team to pick here.

How to make Rams vs. Bengals picks

SportsLine's model is leaning under the total, calling for 41 total points. It has also generated an against-the-spread pick that cashes in over 50% of simulations. You can only get the model's MNF picks at SportsLine

So who wins Bengals vs. Rams on Monday Night Football, and which side of the spread cashes over 50% of the time? Visit SportsLine now to see which side of the Bengals vs. Rams spread to jump on, all from the advanced model that is up more than $7,000 on its NFL picks since its inception, and find out.