AFC South foes meet during the Week 3 NFL schedule when the Houston Texans (0-2) travel to face the Jacksonville Jaguars (1-1) on Sunday. Jacksonville is the defending division champion, and after picking up a division win in Week 1 at Indianapolis, the Jags fell in a hard-fought 17-9 loss against the Chiefs in Week 2. The Texans continue to rebuild. Rookie quarterback C.J. Stroud has put up some big numbers thus far, but they've struggled to keep games competitive as they lost 25-9 to the Ravens in Week 1 and 31-20 to the Colts in Week 2, failing to cover in both games.

Kickoff is scheduled for 1 p.m. ET at EverBank Stadium. Jacksonville is favored by 7.5 points in the latest Texans vs. Jaguars odds, and the over/under for total points scored is 43.5. Before making any Jaguars vs. Texans picks, you need to see the NFL predictions and betting advice from the computer simulation model at SportsLine.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2023 NFL season on an incredible 164-117 run on top-rated NFL picks that dates back to the 2017 season. It is also on an 18-9 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Texans vs. Jaguars and just locked in its picks and NFL Week 3 predictions. You can head to SportsLine now to see the model's picks. Here are several NFL odds and betting lines for Jags vs. Texans:

  • Texans vs. Jaguars spread: Jaguars -7.5
  • Texans vs. Jaguars over/under: 43.5 points
  • Texans vs. Jaguars money line: Jaguars -365, Texans +300
  • Texans vs. Jaguars picks: See picks at SportsLine
  • Texans vs. Jaguars live stream: fubo (try for free)

Why the Jaguars can cover

Jacksonville is the division favorite and it already has a double-digit road win against the Colts, so the Jaguars should be well-positioned to handle this spread at home. Trevor Lawrence has completed 63% of his passes for 457 yards and two touchdowns thus far, while adding 47 yards per game on the ground. Travis Etienne Jr. is the clear lead back and he has a 30-117-1 rushing line on the season. Calvin Ridley Jr., Christian Kirk and Evan Engram have all been reliable targets in the passing game thus far.

Jacksonville's defense has also impressed. The Jags rank fifth in the NFL in total defense through two weeks. And despite the loss, they held the Chiefs in check last week, forcing three turnovers and holding one of the league's top offenses to just 17 points. See which team to pick here.

Why the Texans can cover

Rookie quarterback C.J. Stroud was impressive in Houston's Week 2 loss to the Indianapolis Colts. While a lot of his production came when the game had already been decided, there is still no denying that he showed signs of being a legitimate starting NFL quarterback. Stroud finished the game completing 30 of 47 pass attempts for 384 yards and two TDs.

Houston could get a major boost on its offensive line if All-Pro Laremy Tunsil is able to play. The veteran left tackle missed last week's game with a knee injury, and is listed as questionable heading into Sunday. With Tunsil sidelined, Stroud has been sacked a league-high 11 times this season. See which team to pick here.

How to make Texans vs. Jaguars picks

The model has simulated Texans vs. Jaguars 10,000 times and the results are in. It is leaning Over on the point total, and it's also generated a point-spread pick that hits in well over 50% of simulations. You can only see the model's Texans vs. Jaguars pick at SportsLine.

So who wins Jaguars vs. Texans on Sunday, and which side of the spread hits well over 50% of the time? Visit SportsLine right now to see which side of the Jaguars vs. Texans spread you should be all over Sunday, all from the model on a 164-117 roll on its top-rated NFL picks, and find out.