The Minnesota Timberwolves (15-4) and the San Antonio Spurs (3-16) will link up on Wednesday night in a matchup between teams with the best and worst records in the Western Conference. This is the second meeting of the season between the two, and on Nov. 10, Minnesota edged out San Antonio 117-110. That was the fourth defeat of San Antonio's current 14-game losing streak, while the Timberwolves have won four straight. Anthony Edwards (hip) is listed as questionable for the Wolves, while Jaden McDaniels (ankle) is out.

Tip-off is scheduled for 7:30 p.m. ET at the Target Center in Minneapolis. Minnesota is a 12.5-point favorite in the latest Spurs vs. Timberwolves odds, per SportsLine consensus. The over/under for total points is 230.5. Before making any Timberwolves vs. Spurs picks, you'll want to see the NBA predictions from SportsLine's proven computer model

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past five-plus seasons. The model enters Week 7 of the 2023-24 NBA season on a sizzling 92-50 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. Anyone following it has seen huge returns.

The model has set its sights on Spurs vs. Timberwolves and locked in its NBA predictions. You can head to SportsLine to see its picks. Here are several NBA odds and betting lines for Wolves vs. Spurs:

  • Spurs vs. Timberwolves spread: Minnesota -12.5
  • Spurs vs. Timberwolves Over-Under: 228.5 points
  • Spurs vs. Timberwolves money line: Minnesota -714, San Antonio +503
  • SA: Has hit the Game Total Over in 51 of its last 76 games
  • MIN: Has hit the 1H money line in 50 of its last 85 games
  • Spurs vs. Timberwolves picks: See picks at SportsLine

Why the Timberwolves can cover

Center Rudy Gobert is a towering presence who defends the rim at a high level and consistently piles up rebounds. The 31-year-old is fourth in the NBA in rebounds (11.6), fifth in blocks (2.4), and ninth in field-goal percentage (60.3%). Additionally, he averages 13.3 points per game, and in his last outing, Gobert totaled 26 points, 12 rebounds, and three blocks, which was his third double-double in a row.

Guard Mike Conley provides this squad with a savvy veteran in the backcourt. Conley is a reliable playmaker who creates offense in the half-court. The Ohio State product leads the team in assists (6.2) with 10.4 points per game. On Dec. 2 against the Hornets, the 36-year-old finished with 14 points and 10 assists. He's tallied at least seven assists in each of his last six games. See which team to pick here

Why the Spurs can cover

Center Victor Wembanyama is an absolute beast in a variety of different areas. Wembanyama soars over most players on the floor and can score from all three levels. The 19-year-old thrives as a rebounder and shot-blocker, leading the team in points (19.3), rebounds (9.7), and blocks (2.7). He has finished with 20-plus points in four straight games.

In his last outing, Wembanyama recorded 21 points, 12 rebounds, and four blocks. Meanwhile, forward Keldon Johnson is an effective scorer on the outside or when he's attacking downhill. Johnson logs 16.6 points, 6.5 rebounds, and 4.1 assists per game. He's racked up at least 20 points in six of his last nine games, including on Nov. 30 versus the Atlanta Hawks when Johnson logged 22 points and 11 boards. See which team to pick here.

How to make Spurs vs. Timberwolves picks

The model has simulated Timberwolves vs. Spurs 10,000 times and is leaning Under the total, projecting 218 combined points. It also says one side of the spread hits almost 70% of the time. You can only see the picks at SportsLine.

Who wins Spurs vs. Wolves, and which side of the spread hits almost 70% of the time? Visit SportsLine now to see the picks, all from the model that is on an 92-50 roll on top-rated NBA picks, and find out.