The Syracuse Orange will look to snap their slide on Friday night when they host the Boston College Eagles in an ACC showdown in college football Week 10. The Orange (4-4, 0-4) have lost four straight games since they started Atlantic Coast Conference play. But they have a strong history in the rivalry that dates back to 1924. A 32-23 road victory last year ran their mark to 34-22 in all-time meetings. The Eagles (5-3, 2-2) appear to have settled in after a rocky start and come in on a four-game win streak.

Kickoff on Friday is set for 7:30 p.m. ET at JMA Wireless Dome in Syracuse, N.Y. The latest Boston College vs. Syracuse odds from SportsLine consensus list the Orange as 2.5-point favorites. The over/under for total points scored is set at 50.5. Before locking in any Syracuse vs. Boston College picks, be sure to check out the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a stunning profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Boston College vs. Syracuse and just revealed its picks and predictions. You can visit SportsLine to see the model's CFB picks. Here are several college football odds and trends for Boston College vs. Syracuse: 

  • Boston College vs. Syracuse spread: Orange -2.5
  • Boston College vs. Syracuse over/under: 50.5 points
  • Boston College vs. Syracuse money line: Eagles +125, Orange -147
  • BC: Is 13-13 ATS as an underdog under coach Jeff Hafley (since 2020). 
  • SYR: Is 12-7 ATS as a home favorite under Dino Babers (since 2016).
  • Boston College vs. Syracuse picks: See picks at SportsLine
  • Boston College vs. Syracuse live stream: fubo (try for free)

Why Syracuse can cover

The Orange will be comfortable back in their dome, where they are 3-1 this season. Two of the losses during their slide came against ranked teams, and they are 6-4 in the past 10 meetings. Quarterback Garrett Shrader threw for 285 yards and two TDs as the Orange outgained BC 443-341 in last year's matchup in Chestnut Hill. Shrader has 1,508 passing yards and 316 rushing, accounting for 16 touchdowns. His rushing skill could be available against the Eagles.

Boston College ranks 12th in the ACC in run defense, giving up 164 yards per game on the ground. Running back LeQuint Allen can be trouble as a rusher or receiver, as he leads the team with 25 catches and has 723 total yards. Receivers Damien Alford and Umari Hatcher combined for 46 catches for 745 yards (both average 16.2 per catch). The Syracuse defense has 12 takeaways, and nine players have at least 1.5 sacks for a unit that has totaled 22. See which team to pick here.

Why Boston College can cover

The Eagles started with an overtime loss to Northern Illinois and lost by two points to CFP contender Florida State. They have gotten rolling since a 56-28 rout at the hands of Louisville, with Thomas Castellanos and Kye Robichaux leading the way. Robichaux has 277 rushing yards over the past two games, and quarterback Castellanos can do damage with his arm and legs. The sophomore is fourth in the ACC in total offense, accounting for 278 yards per game.

BC leads the ACC in rushing at 211 yards per game (14th in FBS), and Castellanos has a team-high 673 yards while throwing for 1,549. He has accounted for 20 TDs and has been sacked just 10 times. Robichaux has scored six TDs and receiver Lewis Bond (437 yards) has five. The Eagles allow less than 200 passing yards per game, fifth in the ACC, while the Orange are 13th, giving up 250. Boston College is 3-5 ATS this season but 3-1 ATS as an underdog. See which team to pick here.

How to make Syracuse vs. Boston College picks

SportsLine's model is leaning Under on the point total, projecting the teams to combine for 48 points. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's pick at SportsLine

So who wins Syracuse vs. Boston College, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has notched a profit of well over $2,000 on its top-rated college football spread picks, and find out.