The LSU Tigers (13-12) host the the No. 17 Kentucky Wildcats (18-7) in an SEC matchup on Wednesday. The Wildcats are tied for fourth in the SEC with an 8-4 record in conference play. Meanwhile, LSU is sixth in the SEC (5-7). Kentucky leads the all-time series 93-28 against the Tigers. This is the first matchup of the year between these schools.

Tipoff from Pete Maravich Assembly Center in Baton Rouge is set for 9 p.m. ET. The Wildcats are 6-point favorite in the latest Kentucky vs. LSU odds from SportsLine consensus, while the over/under for total points scored is 163. Before making any LSU vs. Kentucky picks, be sure to see the college basketball predictions and betting advice from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters Week 16 of the 2023-24 season on a 136-89 roll on all top-rated college basketball picks dating back to last season, returning nearly $2,500 for $100 players. It is also off to a sizzling 25-13 start on top-rated spread picks this season. Anyone following has seen huge returns.

Now, the model has set its sights on Kentucky vs. LSU and revealed its CBB picks and predictions. You can head to SportsLine now to see the model's picks. Here are several college basketball odds and trends for LSU vs. Kentucky:

  • Kentucky vs. LSU spread: Wildcats -6
  • Kentucky vs. LSU over/under: 163 points
  • Kentucky vs. LSU money line: Wildcats -259, Tigers +211
  • UK: 15-10 ATS this season 
  • LSU: 11-14 ATS this season 
  • Kentucky vs. LSU picks: See picks at SportsLine

Why Kentucky can cover

Freshman guard Rob Dillingham brings a quick playmaker off the bench. Dillingham has been a creative finisher around the rim with the range to space the floor. The North Carolina native averages 14.7 points, three rebounds and four assists per game. On Feb. 3 versus Tennessee, Dillingham totaled 35 points, four assists and went 6-of-8 from three.

Freshman guard Reed Sheppard is a knockdown shooter who has great court vision to find his teammates. The Kentucky native leads the team in assists (4.1) and steals (2.6) and averages 12.1 points per contest. In the Feb. 10 win over Gonzaga, Sheppard had 21 points, five rebounds and two steals. See which team to pick here

Why LSU can cover

Senior guard Jordan Wright is an all-around threat in the backcourt. Wright has a quick first step while forcing defenders to respect his perimeter shot. The Louisiana native leads the team in both scoring (15) and rebounds (5.1). On Feb. 17 versus South Carolina, Wright had 14 points, seven boards and two blocks.

Senior forward Will Baker brings great size and strength to the floor. The Texas native logs 12.2 points, five rebounds and shoots 52% from the field. He has scored 20-plus points in two of his last five games. In the Feb. 10 loss to Alabama, Baker finished with 24 points and five rebounds. See which team to pick here

How to make LSU vs. Kentucky picks

SportsLine's model is leaning Under on the total, projecting 156 combined points. The model also says one side of the spread hits well over 50% of the time. You can see the picks at SportsLine.

So who wins Kentucky vs. LSU, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the spread you need to jump on, all from the model on a 25-13 roll on top-ranked college basketball spread picks